| Trial Name | Description |
| CE.9 CNS |
Dr. Seth Climans Not Yet Open: LUMOS2: Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS |
| CEC.6 CNS |
Dr. S. Climans N0577 (CODEL): Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q Co-deleted Anaplastic Glioma or Low Grade Glioma. |
| NRG-BN003 |
Dr. Barbara Fisher Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma. |
| INDIGO CNS |
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-Controlled Study of AG-881 in Subjects with Residual or Recurrent Grade 2 Glioma with an IDH1 or IDH2 Mutation |
| ACTION CNS |
Dr. S. Climans The ACTION Study: ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized Double-Blind, Placebo-Controlled, Multicenter Study |